The Evolution of HCT, Part 1: Basics and Outcomes

Estimated Time
1.5 hr(s)

Release Date
Feb 22, 2024

Expiration Date
Feb 21, 2025

Activity Description
Community hematology/oncology practices play a critical role to expand patient access to hematopoietic cell transplantation (HCT) and improve patient outcomes.

This self-guided online training course series consists of five courses designed to present the current state of the science for Hematopoietic Cell Transplantation (HCT) by following the evolution of HCT over time. The series is broken down into major misperceptions or myths about HCT and cellular therapy that are not supported by current research and clinical practice.

This is Part 1 in a 5-part series, including the series introduction, basics of HCT, and major advances in HCT outcomes over time. 


Accreditation and Disclosure Information

Target Audience
This activity is intended for community hematology/oncology practitioners including physicians, APPs, and nurses involved in the diagnosis of HCT-indicated diseases and essential for referral to a transplant center for HCT and cell therapy consultation.

Educational Objectives
After completing this activity, the participant should be better able to:

  • Review the basics of HCT, the role of HLA typing, and a timeline of major advances.
  • Implement strategies to overcome misperceptions about HCT outcomes.
  • Summarize improvements in survival and non-relapse mortality in HCT over time.
  • Examine advances in the prevention of graft-versus-host disease.
  • Recognize the importance of quality of life pre- and post-HCT.
  • Differentiate HCT outcomes by disease and guidelines for when to refer for transplant consultation.

Program Agenda

  • HCT Basics
  • The Role of HLA
  • The Evolution of HCT
  • HCT Misperceptions and Concerns
  • Dispelling Misperceptions, Part 1: HCT Outcomes
  • Improvements in Survival • Advances in GVHD Prevention
  • Quality of Life
  • Outcomes by Disease and Guidelines for Referral

Accreditation, Support and Credit


Joint Accreditation with Commendation Logo In support of improving patient care, this activity has been planned and implemented by Medical Learning Institute, Inc., and NMDP. Medical Learning Institute, Inc. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education
Medical Learning Institute, Inc. (MLI) designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development
Successful completion of this nursing continuing professional development activity will be awarded 1.5 contact hours and no contact hour in the area of pharmacology.

Interprofessional Continuing Education (IPCE) Statement

This activity was planned by and for the healthcare team, and learners will receive 1.5 Interprofessional Continuing Education (IPCE) credits for learning and change.


Support Statement
There is no commercial support associated with this CE activity.

Disclosure & Conflict of Interest Policy
Medical Learning Institute, Inc. and NMDP are committed to providing high quality continuing education to healthcare professionals, as individuals and teams, with a protected space to learn, teach, and engage in scientific discourse free from influence from ineligible companies that may have an incentive to insert commercial bias into education. To that end, MLI requires faculty, presenters, planners, staff, and other individuals who are in a position to control the content of this CE activity to disclose all financial relationships they have had in the past 24 months with ineligible companies as defined by the ACCME, as related to the content of this CE activity, regardless of the amount or their view of the relevance to the education. All identified COI will be thoroughly vetted and mitigated according to MLI policy. These disclosures will be provided to learners prior to the start of the CE activity.

Faculty Disclosures
Planner Laurie Davis, MD, PhD

Baylor College of Medicine
Houston, TX, USA

Laurie Davis, MD, PhD, has no relevant financial relationships with ineligible companies to disclose for this educational activity.

Antonio Vaz De Macedo, MD

Hospital da Polícia Militar de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
Mina Gerais, Brazil

Antonio Vaz De Macedo, MD, has no relevant financial relationships with ineligible companies to disclose for this educational activity.

Planning Committee and Content/Peer Reviewers
The planners and content/peer reviewers from Medical Learning Institute, Inc., the accredited provider, and NMDP, the joint provider, do not have any relevant financial relationships to disclose with ineligible companies unless listed below.

Disclosure of Unlabeled Use
This educational activity may contain discussions of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this CE activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the CE activity are those of the presenters and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this CE activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this CE activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

Method of Participation
There are no fees for participating in or receiving credit for this CE activity. In order to receive credit, learners must participate in the entire CE activity, complete the post-test and activity evaluation form and your certificate of credit will be generated. A passing score of 70% or higher is needed to obtain credit. You will receive your certificate from Medical Learning Institute, Inc.

For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

If you have questions regarding your certificate, please contact Mary Vu via email at

About this Activity
Medical Learning Institute, Inc. and NMDP are responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this CE activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of Medical Learning Institute, Inc. or any of its partners, providers, and/or supporters.

Copyright © 2024 Medical Learning Institute, Inc. All Rights Reserved.


Download the course resources from within the presentation lesson.