Improving Survival in First-Line Metastatic NSCLC with Dual Checkpoint Blockade: Real-world Applications in Clinical Practice / Activity 2

Estimated Time
0.50 hr

Release Date
Feb 17, 2023

Expiration Date
Sep 30, 2024

This educational initiative is designed for community-based oncology clinicians (physicians, nurse practitioners [NPs], physician assistants [PAs], pharmacists, and nurses) to enhance outcomes for individuals with who provide care for individuals with mNSCLC. This interactive online activity uses the game-based platform Kahoot! to test participant ability to identify and apply key learning points while competing against their colleagues. Expert faculty will discuss the emerging efficacy and safety data for CTLA-4 inhibitor combination regimens in metastatic NSCLC (mNSCLC) and explore strategies to identify patients who would most benefit from these therapies through the use of biomarkers. Additionally, there will be an in-depth discussion regarding approaches to effectively collaborate with other clinicians and mNSCLC patients to provide cost-effective, equitable, and inclusive care for patients of all socioeconomic and racial/ethnic backgrounds. Join us for Part 2 of this question and answer based educational activity, Improving Survival in First-line Metastatic NSCLC with Dual Checkpoint Blockade: Real-world Applications in Clinical Practice to apply the evidence to real-world patient cases!


Accreditation and Disclosure Information

This CE activity is intended for community-based oncology clinicians including physicians, advanced practice providers (APPs, ie, NPs and PAs), nurses, and pharmacists who provide care for individuals with mNSCLC.

After completing this CE activity, the participant should be better able to:

  • Evaluate emerging efficacy and safety data regarding CTLA-4 inhibitor-containing regimens in mNSCLC
  • Plan strategies to use current and emerging biomarkers to select mNSCLC patients who are likely to benefit from therapy with dual PD-1/CTLA-4 checkpoint blockade
  • Collaborate with members of other disciplines and professions to provide cutting-edge, cost-effective, equitable, and inclusive care for patients with mNSCLC
Joint Accreditation with Commendation logoIn support of improving patient care, Medical Learning Institute, Inc. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician Continuing Medical Education
Medical Learning Institute, Inc. (MLI) designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nursing Continuing Professional Development
Successful completion of this nursing continuing professional development activity will be awarded 0.5 contact hour and 0.5 contact hour in the area of pharmacology.
Continuing Pharmacy Education
Medical Learning Institute, Inc. designates this continuing education activity for 0.5 (0.05 CEU) contact hour of the Accreditation Council for Pharmacy Education.
Universal Activity Number: JA0007322-0000-23-016-H01-P
Type of Activity: Knowledge 
AAPA Credit Designation Statement
Medical Learning Institute, Inc. has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.5 AAPA Category 1 CME credits. Approval is valid until February 16, 2024. PAs should only claim credit commensurate with the extent of their participation.
Interprofessional Continuing Education (IPCE) Statement
This activity was planned by and for the healthcare team, and learners will receive 0.5 Interprofessional Continuing Education (IPCE) credits for learning and change.
This activity is supported by an independent educational grant from AstraZeneca.
Medical Learning Institute, Inc., is committed to providing high quality continuing education to healthcare professionals, as individuals and teams, with a protected space to learn, teach, and engage in scientific discourse free from influence from ineligible companies that may have an incentive to insert commercial bias into education.  To that end, MLI requires faculty, presenters, planners, staff, and other individuals who are in a position to control the content of this CE activity to disclose all financial relationships they have had in the past 24 months with ineligible companies as defined by the ACCME, as related to the content of this CE activity, regardless of the amount or their view of the relevance to the education. All identified COI will be thoroughly vetted and mitigated according to MLI policy. These disclosures will be provided to learners prior to the start of the CE activity.
Narjust Florez, MD
Associate Director of The Cancer Care Equity Program
Thoracic Oncologist – Lowe Center For Thoracic Oncology
Dana-Farber Cancer Institute
Assistant Professor of Medicine, Harvard Medical School
Boston, MA
Narjust Florez, MD, has a financial interest/relationship or affiliation in the form of:
Advisory Board/Consultant: AstraZeneca, Bristol Myers Squibb, Daiichi Sankyo, Janssen, Merck, Pfizer
Speakers’ Bureau: NeoGenomics
Stephen M. Schleicher, MD, MBA
Medical Oncologist 
Chief Medical Officer 
Tennessee Oncology
Nashville, TN
Stephen M. Schleicher, MD, MBA, has no relevant financial relationships with ineligible companies to disclose for this educational activity.
Heather Wakelee, MD, FASCO
Professor of Medicine and Chief 
Division of Oncology
Interim Medical Director, Stanford Cancer Center
Deputy Director, Stanford Cancer Institute
President, International Association for the Study of Lung Cancer (IASLC)
Stanford, CA
Heather Wakelee, MD, FASCO, has a financial interest/relationship or affiliation in the form of:
Research Grant: ACEA Biosciences, Arrys Therapeutics, AstraZeneca/MedImmune, Bristol Myers Squibb, Clovis Oncology, Genentech/Roche, Merck, Novartis, Seagen, Xcovery, Helsinn
The following relationships have ended within the last 24 months:
Advisory Board/Consultant: Mirati
All of the relevant financial relationships of individuals for this activity have been mitigated.
The planners and content/peer reviewers from Medical Learning Institute, Inc., the accredited provider, do not have any relevant financial relationship(s) to disclose with ineligible companies unless listed below.
This educational activity may contain discussions of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this CE activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the CE activity are those of the presenters and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this CE activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this CE activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
There are no fees for participating in or receiving credit for this CE activity. In order to receive credit, learners must participate in the entire CE activity, complete the activity evaluation form and your certificate of credit will be generated. You will receive your certificate from Medical Learning Institute, Inc.

For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

If you have questions regarding your certificate, please contact Mary Vu via email at

For Pharmacists, MLI will accept your completed evaluation form for up to 30 days post-activity and will report your participation to the NABP only if you provide your NABP e-Profile number and DOB (MM/DD). Within 6 weeks, you can view your participation record at the NABP website:

Medical Learning Institute, Inc. is responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this CE activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions. The preparation of this activity is supported by educational grants subject to written agreements that clearly stipulate and enforce the editorial independence of Medical Learning Institute, Inc.
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