As the treatment armamentarium for patients with hemophilia continues to expand, there is an urgent need for healthcare providers to stay up-to-date on the latest advances so that they are prepared to integrate them into clinical practice. To bridge this gap, this interactive educational activity will provide a review of the science surrounding new and emerging hemophilia treatments and their mechanisms of action; recent safety and efficacy data from key clinical trials; and novel dosing strategies to mitigate adverse events. Engaging case-based discussions and insights on addressing common patient barriers and clinical challenges will be explored by expert faculty, including a guest spotlight offering the early perspective. Thus, this educational initiative is designed to equip providers with the necessary tools to effectively navigate new and novel therapies, overcome patient-level barriers, and optimize adherence for improved patient outcomes.
Speakers
Tammuella E. Chrisentery-Singleton, MD
As Chief Science Officer (CSO) for ATHN, Tammuella Chrisentery-Singleton, MD, works at the strategic and policy level to inform the scientific direction of ATHN. She works across the organization to define, develop, and implement ATHN’s science and research capabilities as well as to ensure ATHN’s commitment to public health. Dr. Singleton is board-certified in general pediatrics and pediatric hematology/oncology. Her areas of special interest include sickle cell disease, rare blood disorders, gene therapy, and musculoskeletal ultrasound in hemophilia patients. She has authored numerous publications and led more than 60 clinical trials and research studies—including serving as the principal investigator for ATHN 16: Safety of SEVENFACT® for the Treatment of Bleeding Events in Patients with Hemophilia A or B with Inhibitor. Before joining ATHN, Dr. Singleton was the Chief of Pediatric Hematology and Director of the Hemophilia Treatment Center for the Mississippi Center for Advanced Medicine. She also previously served as the Chief of Pediatric Hematology and Oncology, the Director of the Sickle Cell Center of South Louisiana, and the Associate Director of the Louisiana Center for Bleeding and Clotting Disorders at the Tulane University School of Medicine/Tulane Hospital for Children.
Alan E. Mast, MD, PhD
Dr. Mast is a Senior Investigator and Leader of the Thrombosis and Hemostasis Program at the Versiti Blood Research Institute in Milwaukee Wisconsin where he holds the Walter A. Schroeder Endowed Chair for Blood Research. Dr. Mast received a BS in biochemistry at the University of Illinois and MD and PhD degrees from Duke University. He performed residency training in Laboratory Medicine at Washington University in St. Louis. He has directed a research laboratory that focuses on the biology of tissue factor pathway inhibitor for over 25 years.
Allison P. Wheeler, MD, MSCI
Originally from Boston MA, Allison P Wheeler received her medical training at the University of Massachusetts. She subsequently completed her pediatric hematology / oncology and blood banking / transfusion medicine fellow training at Vanderbilt University Medical Center. She has worked at faculty in pediatrics and pathology at Vanderbilt since the completion of her training in 2014. Allison splits her clinical time between pediatric patients with hemostatic and thrombotic disorders, and is the co-medical director of the coagulation laboratory. She is also the director of research for benign hematology at Vanderbilt with a robust collaborative research portfolio and a personal research interest in women with heavy menstrual bleeding. Her academic work has expanded to also include investigation into the use of COVID Convalescent Plasma (CCP) as a treatment option for COVID-19, vaccine safety, and investigation of diversity, equity, and inclusion in medicine. Allison spends as much time outside as she can when she isn’t at work, she loves running and hiking, and her family – husband Scott and 3 kids (Finn (20), Darby (17) and Nat (5)). In 2024 she worked with Dignity Matters, a period poverty non-profit organization in Boston, to participate in the Boston Marathon this April 15th with a charity bib.
Shannon C. Walker, MD
Assistant Professor, Vanderbilt University Medical Center
Department of Pathology, Microbiology, and Immunology – Transfusion Medicine
Department of Pediatrics – Vanderbilt Vaccine
Research Program and Pediatric Hematology/Oncology
Nashville, TN
Dr. Shannon Walker received undergraduate degrees in Biology and Microbiology from the University of Georgia in Athens, GA and attended medical school at the Wake Forest School of Medicine in Winston-Salem, NC. She completed her pediatric residency, pediatric hematology/oncology fellowship, and transfusion medicine fellowship at Vanderbilt University Medical Center in Nashville, TN. She is currently at Vanderbilt as an Assistant Professor in the Department of Pathology, Microbiology, and Immunology with a joint appointment in the Department of Pediatrics. Her research focuses on pediatric hemostasis and thrombosis, predictive modeling, clinical trial design and execution, and hematology-related vaccine complications
Accreditation and Disclosure Information
Educational Objectives
After completing this activity, the participant should be better able to:
- Appropriately select hemophilia treatment based on the latest clinical evidence on new and emerging therapies in accordance with clinical guidelines
- Accurately identify symptoms and potential adverse events associated with the various treatment modalities for patients with hemophilia
- Skillfully employ shared decision-making to screen for and address QoL concerns for patients with hemophilia
- Formulate strategies to surmount barriers that hinder the delivery of optimal patient care across the continuum, including patients in rural communities, of female sex, and mild disease
Program Agenda
- The Right Treatment for the Right Patient: Integrating Novel Therapies into Clinical Practice
- Managing the Diverse Account of Adverse Events With Treatment
- Elevating Patient Care: Addressing Barriers and Supporting Patients in the Care Continuum
Target Audience
This activity is intended for hematologists/oncologists, PAs, NPs, nurses, pharmacists, and individuals that practice at hemophilia treatment centers (HTC) engaged in the care of patients with hemophilia.
Accreditation, Support and Credit
In support of improving patient care, Medical Learning Institute, Inc. is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician Continuing Medical Education
Medical Learning Institute, Inc. (MLI) designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
MOC Statement
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC point in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Participation information will be shared through the ACCME's Program and Activity Reporting System (PARS).
Physician Associate
Medical Learning Institute, Inc. has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit. Approval is valid until May 14, 2025. PAs should only claim credit commensurate with the extent of their participation
Nursing Continuing Professional Development
Successful completion of this nursing continuing professional development activity will be awarded 1.0 contact hour and 0.66 contact hour in the area of pharmacology.
Continuing Pharmacy Education
Medical Learning Institute, Inc. designates this continuing education activity for 1.0 contact hour (0.1 CEU) of the Accreditation Council for Pharmacy Education.
Universal Activity Number: JA0007322-0000-24-048-H01-P
Type of Activity: Application
Interprofessional Continuing Education (IPCE) Statement
This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change.
Commercial Support Statement
This activity is supported by an educational grant from Novo Nordisk Inc.
Disclosure & Conflict of Interest Policy
Medical Learning Institute, Inc. is committed to providing high quality continuing education to healthcare professionals, as individuals and teams, with a protected space to learn, teach, and engage in scientific discourse free from influence from ineligible companies that may have an incentive to insert commercial bias into education. To that end, MLI requires faculty, presenters, planners, staff, and other individuals who are in a position to control the content of this CE activity to disclose all financial relationships they have had in the past 24 months with ineligible companies as defined by the ACCME, as related to the content of this CE activity, regardless of the amount or their view of the relevance to the education. All identified COI will be thoroughly vetted and mitigated according to MLI policy. These disclosures will be provided to learners prior to the start of the CE activity.
Faculty Disclosures
Planner/Presenter
Tammuella E. Chrisentery-Singleton, MD
Chief, Pediatric Hematology
Chief Science Officer
American Hemostasis and Thrombosis Network
Rochester, NY
Co-Director, Hemostasis & Thrombosis Program
Ochsner Clinic Foundation
New Orleans, LA
Tammuella E. Chrisentery-Singleton, MD, has a financial interest/relationship or affiliation in the form of: Consultant/Advisor: Octapharma, Bayer, Novo Nordisk, CSL Behring, Kedrion, Genentech, BioMarin, Takeda, HEMA Biologics, Pfizer
Speakers’ Bureau: Octapharma, Bayer, Novo Nordisk, CSL Behring, Kedrion, Genentech, BioMarin, Takeda, HEMA Biologics, Pfizer
Planner/Presenter
Alan E. Mast, MD, PhD
Leader, Thrombosis and Hemostasis Program
Walter A. Schroeder Endowed Chair for Blood Research
Senior Investigator and Program Leader
Versiti Blood Research Institute
Milwaukee, WI
Alan E. Mast, MD, PhD, has a financial interest/relationship or affiliation in the form of:
Consultant/Advisor: Novo Nordisk
Research Funding: Novo Nordisk
Planner/Presenter
Allison P. Wheeler, MD, MSCI
Associate Professor
Vanderbilt University Medical Center
Departments of Clinical Pathology & Pediatric Hematology
Director of Research for Benign Hematology
Nashville, TN
Allison P. Wheeler, MD, MSCI, has a financial interest/relationship or affiliation in the form of:
Consultant/Advisor: CSL Behring, Bayer, Novo Nordisk, Canofi, Genentech, Takeda, Pfizer, Vega Therapeutics
Research Funding: Octapharma, Novo Nordisk, Sanofi, CSL Behring, Vega Therapeutics
Guest Commentator
Shannon C. Walker, MD
Assistant Professor, Vanderbilt University Medical Center
Department of Pathology, Microbiology, and Immunology – Transfusion Medicine
Department of Pediatrics – Vanderbilt Vaccine Research Program and Pediatric Hematology/Oncology
Nashville, TN
Shannon C. Walker, MD, has no relevant financial relationships with ineligible companies to disclose for this educational activity.
All of the relevant financial relationships of individuals for this activity have been mitigated.
Planning Committee and Content/Peer Reviewers
The planners and content/peer reviewers from Medical Learning Institute, Inc., the accredited provider, do not have any relevant financial relationships to disclose with ineligible companies unless listed below.
Disclosure of Unlabeled Use
This educational activity may contain discussions of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this CE activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the CE activity are those of the presenters and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this CE activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this CE activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.
Method of Participation
There are no fees for participating in or receiving credit for this CE activity. In order to receive credit, learners must participate in the entire CE activity, complete the activity evaluation form and your certificate of credit will be generated. You will receive your certificate from Medical Learning Institute, Inc.
For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.
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For Pharmacists, MLI will accept your completed evaluation form for up to 30 days post-activity and will report your participation to the NABP only if you provide your NABP e-Profile number and DOB (MM/DD). Within 6 weeks, you can view your participation record at the NABP website: https://nabp.pharmacy/.
About This Activity
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